2021年博士毕业于荷兰格罗宁根大学，2021-2025年在瑞士日内瓦大学任科研助理。长期从事基于质谱的多组学研究，专注于蛋白组学、代谢组学、多肽及蛋白化学等领域。致力于开发高效、精准的蛋白、肽段及代谢物的定性与定量分析方法，以揭示与疾病相关的关键生物分子机制。以第一或通讯作者在 Analytical Chemistry、Analytica Chimica Acta、Journal of Proteome Research、Mass Spectrometry Reviews 等国际权威期刊发表多篇研究论文。

质谱分析，蛋白组学

(1) Xiaobo Tian; Marcel P. de Vries; Susan W. J. Visscher; Hjalmar P. Permentier; Rainer

Bischoff ; Selective Maleylation-Directed Isobaric Peptide Termini Labeling for Accurate Proteome

Quantification, Analytical Chemistry, 2020, 92(11): 7836-7844;

(2) Xiaobo Tian; Marcel P. de Vries; Hjalmar P. Permentier; Rainer Bischoff ; A Versatile

Isobaric Tag Enables Proteome Quantification in Data-Dependent and Data-Independent Acquisition Modes, Analytical Chemistry, 2020, 92(24): 16149-16157;

(3) Xiaobo Tian; Marcel P. de Vries; Hjalmar P. Permentier; Rainer Bischoff ; The Ac-IP tag

enables multiplexed proteome quantification in data-independent acquisition mode, Analytical

Chemistry, 2021, 93(23): 8196-8202;

(4) Xiaobo Tian; Gérard Hopfgartner ; Improved quantification of carbonyl sub-metabolome by

liquid chromatography mass spectrometry using a fragment controlled multiplexed isotopic tag,

Analytica Chimica Acta, 2024, 1287: 342117;

(5) Xiaobo Tian; Patrick Mueller; Piotr Sosnowski; Fang Li; Dongliang Guan; Charlotte

Jacquet; Gérard Hopfgartner ; Perturbation-Modulated Native Mass Spectrometry Excludes a

Nonspecific Drug Target Protein Binder Based on Conformation Stability Change, Analytical

Chemistry, 2025, 97(12): 6767-6770.