博士、教授、主任医师，硕士生导师。现任浙江省肿瘤医院麻醉与疼痛康复科主任、麻醉教研室主任、麻醉与围术期医学实验室主任、三级教授，兼任中国抗癌协会肿瘤麻醉与镇痛专业委员会副主任委员、中国心胸血管麻醉学会胸科麻醉分会副主任委员、中华医学会麻醉学分会围术期大数据学组副组长、浙江省医学会疼痛学分会常委、浙江省医学会麻醉学分会委员、浙江省医师协会麻醉医师分会委员等。目前横/纵项课题经费合计650万。

以第一作者及通讯作者（含共同）在Cell Death Dis、Front Oncol、J Cell Physiol、Exp Cell Res、Biomed Pharmacother等领域内知名期刊发表发表SCI论文20余篇。[1] Yang F, Hua Q, Zhu X, Xu P. Surgical stress induced tumor immune suppressive environment. Carcinogenesis. 2024 Apr 12;45(4):185-198.

[2] Hua Q, Sun Z, Liu Y, Shen X, Zhao W, Zhu X, Xu P. KLK8 promotes the proliferation and metastasis of colorectal cancer via the activation of EMT associated with PAR1. Cell Death Dis. 2021 Sep 22;12(10):860. 

[3] Hua Q, Li T, Liu Y, Shen X, Zhu X, Xu P. Upregulation of KLK8 Predicts Poor Prognosis in Pancreatic Cancer. Front Oncol. 2021 Jul 30;11:624837.

[4] Hua Q, Xu W, Shen X, Tian X, Zhang H, Li Y, Xu P. Dynamic changes of plasma extracellular vesicle long RNAs during perioperative period of colorectal cancer. Bioengineered. 2021 Dec;12(1):3699-3710.

[5] Zhao YJ, Lv H, Xu PB, Zhu MM, Liu Y, Miao CH, Zhu Y. Protective effects of oridonin on the sepsis in mice. Kaohsiung J Med Sci. 2016 Sep;32(9):452-7.

[6] Shen X, Zhou C, Hua Q, Yang L, Zhao W, Xu P. Impact of operation duration on short-term and long-term prognosis in patients undergoing radical colorectal surgery. J Cancer. 2022 Jan 16;13(4):1160-1167.

[7] Zhao W, Shen X, Hua Q, Yang L, Zhou R, Zhou C, Xu P. Red cell distribution width-a potential prognostic indicator for colorectal cancer patients after radical resection in China. J Gastrointest Oncol. 2023 Aug 31;14(4):1746-1758.

[8] Xu P, He H, Gu Y, Wang Y, Sun Z, Yang L, Miao C. Surgical trauma contributes to progression of colon cancer by downregulating CXCL4 and recruiting MDSCs. Exp Cell Res. 2018 Sep 15;370(2):692-698.

[9] Sun Z, Du C, Xu P, Miao C. Surgical trauma-induced CCL18 promotes recruitment of regulatory T cells and colon cancer progression. J Cell Physiol. 2019 Apr;234(4):4608-4616.

[10] Xu P, Zhang P, Sun Z, Wang Y, Chen J, Miao C. Surgical trauma induces postoperative T-cell dysfunction in lung cancer patients through the programmed death-1 pathway. Cancer Immunol Immunother. 2015 Nov;64(11):1383-92.

[11] Xu PB, Mao YF, Meng HB, Tian YP, Deng XM. STY39, a novel alpha-melanocyte-stimulating hormone analogue, attenuates bleomycin-induced pulmonary inflammation and fibrosis in mice. Shock. 2011 Mar;35(3):308-14.

[12] Lin ZY, Xu PB, Yan SK, Meng HB, Yang GJ, Dai WX, Liu XR, Li JB, Deng XM, Zhang WD. A metabonomic approach to early prognostic evaluation of experimental sepsis by (1)H NMR and pattern recognition. NMR Biomed. 2009 Jul;22(6):601-8.

[13] Xu PB, Lin ZY, Meng HB, Yan SK, Yang Y, Liu XR, Li JB, Deng XM, Zhang WD. A metabonomic approach to early prognostic evaluation of experimental sepsis. J Infect. 2008 Jun;56(6):474-81.

[14] Chen W, Xu Y, Zhong J, Wang H, Weng M, Cheng Q, Wu Q, Sun Z, Jiang H, Zhu M, Ren Y, Xu P, Chen J, Miao C. MFHAS1 promotes colorectal cancer progress by regulating polarization of tumor-associated macrophages via STAT6 signaling pathway. Oncotarget. 2016 Nov 29;7(48):78726-78735.

[15] Sun Z, Mao A, Wang Y, Zhao Y, Chen J, Xu P, Miao C. Treatment with anti-programmed cell death 1 (PD-1) antibody restored postoperative CD8+ T cell dysfunction by surgical stress. Biomed Pharmacother. 2017 May;89:1235-1241.

[16] Wang J, Yin Y, Zhu Y, Xu P, Sun Z, Miao C, Zhong J. Thoracic epidural anaesthesia and analgesia ameliorates surgery-induced stress response and postoperative pain in patients undergoing radical oesophagectomy. J Int Med Res. 2019 Dec;47(12):6160-6170.

[17] Yan X, Li W, Yang L, Dong W, Chen W, Mao Y, Xu P, Li D, Yuan H, Li YH. MiR-135a Protects Vascular Endothelial Cells Against Ventilator-Induced Lung Injury by Inhibiting PHLPP2 to Activate PI3K/Akt Pathway. Cell Physiol Biochem. 2018;48(3):1245-1258.

[18] Xu PB, Lou JS, Ren Y, Miao CH, Deng XM. Gene expression profiling reveals the defining features of monocytes from septic patients with compensatory anti-inflammatory response syndrome. J Infect. 2012 Nov;65(5):380-91.

[19] Wang X, Xie W, Gan S, Wang T, Chen X, Su D, Sun J, Lin J, Wu F, Xu P, Miao C, Yan M, Zhu S, Zhai B, Sun Y, Yu W, Tian J. Effects of general anesthesia versus local anesthesia in primary hepatocellular carcinoma patients presenting for thermal ablation surgery: a multiple center retrospective cohort study with propensity score matching. Ann Transl Med. 2020 Mar;8(6):277.

[20] Xu P, Sun Z, Wang Y, Miao C. Long-term use of indomethacin leads to poor prognoses through promoting the expression of PD-1 and PD-L2 via TRIF/NF-κB pathway and JAK/STAT3 pathway to inhibit TNF-α and IFN-γ in hepatocellular carcinoma. Exp Cell Res. 2015 Sep 10;337(1):53-60.