代表论著
1.Meng Zhao, Michael T. Woodside, Mechanical strength of RNA knot in Zika virus protects against cellular defenses. Nature Chemical Biology, 2021, 17, 975-981.
This work has been highlighted in various journals and across social media platforms, as detailed below:
Nature 2021, 595, 474: Tied in knots: Zika virus tangles are the most stable RNA known.
Science, 2021, 373, 638: RNA knots provide resistance.
Nat. Chem. Biol. 2021, 17, 933-934: Untying knots with force.
Sci. Transl. Med. DOI: 10.1126/scitranslmed.abl8161: Viral Knots.
Phys.Org https://phys.org/news/2021-07-biophysicists-mechanism-zika-virus-dangerous.html
Mirage News https://www.miragenews.com/biophysicists-target-mechanism-that-makes-zika-596326/
UofA Folio https://www.ualberta.ca/folio/2021/07/biophysicists-target-mechanism-that-makes-zika-virus-so-dangerous.html
中文报道 https://mp.weixin.qq.com/s/jFGAj6Xvgu-rO59iQJKEbA
2.Krishna Neupane*, Meng Zhao*, Aaron Lyons, Sneha Munshi, Sandaru M. Ileperuma, Dustin B. Ritchie, Noel Q. Hoffer, Abhishek Narayan, Michael T. Woodside, Structural dynamics of single SARS-CoV-2 pseudoknot molecules reveal topologically distinct conformers. Nature Communications, 2021, 12, 4749.
3.Sara I. Omar, Meng Zhao, Rohith V. Sekar, Sahar A. Moghadam, Jack A. Tuszynski, Michael T. Woodside, Modeling the structure of the frameshift-stimulatory pseudoknot in SARS-CoV-2 reveals multiple possible conformers, PLoS Computational Biology, 2021, 17, e1008603.
4.Meng Zhao, Richard Börner, Roland K. O. Sigel, Eva Freisinger, Site-specific dual-color labeling of long RNAs, RNA Chaperones: Methods and Protocols, Springer US, 2020, 253-270 (book chapter).
5.Meng Zhao, Fabio D. Steffen, Richard Börner, Michelle F. Schaffer, Roland K O Sigel, Eva Freisinger, Site-specific dual-color labeling of long RNAs for single-molecule spectroscopy, Nucleic Acids Research, 2018, 46, e13.
6.Meng Zhao, Haibo Wang, Liang-Nian Ji, Zong-Wan Mao, Insights into metalloenzyme microenvironments: biomimetic metal complexes with a functional second coordination sphere, Chemical Society Reviews, 2013, 42, 8360-8375.
7.Meng Zhao, Han-Lu Wang, Li Zhang, Cong Zhao, Liang-Nian Ji, Zong-Wan Mao, Unexpected phosphodiesterase activity at low pH of a dinuclear copper–β-cyclodextrin complex, Chemical communications, 2011, 47, 7344-7346.
8.Meng Zhao, Li Zhang, Huo-Yan Chen, Han-Lu Wang, Liang-Nian Ji, Zong-Wan Mao, Effect of hydrophobic interaction cooperating with double Lewis acid activation in a zinc (II) phosphodiesterase mimic, Chemical communications, 2011, 47, 7344-7346.
9.Meng Zhao, Cong Zhao, Xue-Qin Jiang, Liang-Nian Ji, Zong-Wan Mao, Rapid hydrolysis of phosphate ester promoted by Ce (IV) conjugating with a β-cyclodextrin monomer and dimer. Dalton Transactions, 2012, 41, 4469-4476.
10.Meng Zhao, Shan-Shan Xue, Xue-Qin Jiang, Limin Zheng, Liang-Nian Ji, Zong-Wan Mao, Phosphate ester hydrolysis catalyzed by a dinuclear cobalt (II) complex equipped with intramolecular β-cyclodextrins. Journal of Molecular Catalysis A: Chemical, 2015, 396, 346-352.