入选国家优秀青年科学基金（海外）项目、浙江省海外高层次人才创新长期项目和浙江省卫生高层次创新人才项目。2009年和2014年分别获浙江大学学士和博士学位，随后赴美国加州大学洛杉矶分校（UCLA）开展博士后研究工作；2019年升任项目科学家。2020年全职加入中国科学院杭州医学研究所，主持国家重点研发计划（创新特区）、国家自然科学基金、浙江省自然科学基金重大项目（青年原创项目）等项目。

核酸适体靶向药物、mRNA药物与疫苗、智能纳米药物载体、纳米-生物界面效应等研究, 旨在为癌症、重大传染性疾病等提供更加安全、有效的防治手段。

主持国家重点研发计划（创新特区）、国家自然科学基金、浙江省自然科学基金重大项目（青年原创项目）等项目

累计发表SCI论文90余篇，总引用5000余次，其中以第一作者与通讯作者在Journal of Clinical Investigation (JCI), ACS Nano，Advanced Science, Nature Communications，Matter 等国际知名学术期刊上发表论文30余篇。 代表性论著： 1.Ma, R.; Li, Y.; Wei, Y.; Zhou, J.; Ma, J.; Zhang, M.; Tu, J.; Jiang, J.; Xie, S.; Tan, W.; Liu, X*. The dynamic process of mRNA delivery by lipid nanoparticles in vivo. Nano Today 2024, 57, 102325. 2.Dong, S. #; Feng, Z. #; Ma, R.; Zhang, T.; Jiang, J.; Li, Y.; Zhang, Y.; Li, S.; Liu, X.; Liu, X.*; Meng, H*. Engineered Design of a Mesoporous Silica Nanoparticle-Based Nanocarrier for Efficient mRNA Delivery in Vivo. Nano Letters 2023, 23, 2137-2147. 3.Liu, X. #; Xie, X. #; Jiang, J. #; Lin, M.; Zheng, E.; Qiu, W.; Yeung, I.; Zhu, M.; Li, Q.; Xia, T.; Meng, H.* Use of Nanoformulation to Target Macrophages for Disease Treatment. Advanced Functional Materials 2021, 31, 2104487. 4.Liu, X.; Jiang, J.; Chang, C. H.; Liao, Y. P.; Lodico, J. J.; Tang, I.; Zheng, E.; Qiu, W.; Lin, M.; Wang, X.; Ji, Y.; Mei, K. C.; Nel, A. E.* and Meng, H*. Development of Facile and Versatile Platinum Drug Delivering Silicasome Nanocarriers for Efficient Pancreatic Cancer Chemo-Immunotherapy. Small 2021, e2005993. 5.Liu, X.; Jiang, J.; Liao, Y-P.; Tang, I.; Zheng, E.; Qiu, W.; Lin, M.; Wang, X.; Ji, Y.; Mei, K-C.; Liu, Q.; Chang, C. H.; Wainberg, Z. A.; Nel, A. E. * and Meng, H*, Combination Chemo‐Immunotherapy for Pancreatic Cancer Using the Immunogenic Effects of an Irinotecan Silicasome Nanocarrier Plus Anti-PD-1, Advanced Science 2021, 8, 2002147. 6.Ji, Y. #; Liu, X. #; Li, J.; Xie, X.; Huang, M.; Jiang, J.; Liao, Y-P.; Donahue, T.; Meng, H. *, Use of ratiometrically designed nanocarrier targeting CDK4/6 and autophagy pathways for effective pancreatic cancer treatment, Nature Communications 2020, 4249. 7.Liu, X.#; Jiang, J.#; Chan, R.; Ji, Y.; Lu, J.; Liao, Y-P.; Okene, M.; Lin, J.; Lin, P.; Chang, C.H.; Wang, X.; Tang, I.; Zheng, E.; Qiu, W.; Wainberg, Z. A.; Nel, A. E.*; Meng, H.*, Improved Efficacy and Reduced Toxicity Using a Custom-Designed Irinotecan-Delivering Silicasome for Orthotopic Colon Cancer. ACS Nano 2019, 13, 38-53. 8.Liu, X.; Lin, P.; Perrett, I.; Lin, J.; Liao, Y.-P.; Chang, C. H.; Jiang, J.; Wu, N.; Donahue, T.; Wainberg, Z.; Nel, A. E.*; Meng, H.*, Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer. Journal of Clinical Investigation 2017, 127, 2007–2018. 9.Liu, X.; Situ, A.; Kang, Y.; Villabroza, K. R.; Liao, Y.-P.; Chang, C. H.; Donahue, T.; Nel, A. E.*; Meng, H.*, Irinotecan delivery by lipid-coated mesoporous silica nanoparticles show improved efficacy and safety over liposomes for pancreatic cancer. ACS Nano 2016, 10, 2702–2715. 10.Liu, X.; Chen, Y.; Li, H.; Huang, N.; Jin, Q.; Ren, K.; Ji, J.*, Enhanced retention and cellular uptake of nanoparticles in tumor by controlling their aggregation behavior. ACS Nano 2013, 7, 6244-6257. 11.Liu, X.; Cao, J. M.; Li, H.; Li, J. Y.; Jin, Q.; Ren, K. F.; Ji, J.*, Mussel-inspired polydopamine: a biocompatible and ultrastable coating for nanoparticles in vivo. ACS Nano 2013, 7, 9384-9395.

作为核心发明人，申请及获授权中国、美国专利10余项，并开展相应临床转化研究。